Dolly, the first mammal cloned from an adult cell, was born 5 July 1996. But she was created five months earlier, in a small room at the Roslin Institute, outside Edinburgh, UK. Walker and Ritchie were part of a project at the Roslin Institute and spin-off PPL Therapeutics, aiming to make precise genetic changes to farm animals. The scientific team, led by Roslin embryologist Ian Wilmut, reasoned that the best way to make these changes would be to tweak the genome of a cell in culture and then transfer the nucleus to a new cell. They speak to Nature magazine about the story from incubation in a bra to an afterlife under glass, how a cloned sheep attained celebrity status.
Dolly at 20: The inside story on the world’s most famous sheep