British scientists have begun testing a radically new approach to treating schizophrenia based on emerging evidence that it could be a disease of the immune system.
The trial builds on more than a decade’s work by Oliver Howes, a professor of molecular psychiatry at the MRC London Institute of Medical Sciences and a consultant psychiatrist at the Maudsley Hospital in south London. Howes’s team is one of several worldwide to have uncovered evidence that abnormalities in immune activity in the brain may lie at the heart of the illness – for some patients, at least.
“In the past, we’ve always thought of the mind and the body being separate, but it’s just not like that,” said Howes. “The mind and body interact constantly and the immune system is no different. It’s about changing the way we think about mental illnesses.”